Yes you can.According to the specs your board should be ready for RAIDs 0, 1, 5, or 10.The Seagate 12 series are excellent drives so you will get a lot of speed out of these in RAID-0.I do recommend that you short stroke the array and install your OS and favorite apps on the faster parts of the array:http://www.my630i.com/viewtopic.php?f=4&t=3722&start=10Use a free program like HD Tune and analyze your setup.Make sure you use a good backup program like Acronis to backup your entire array.***