Yes.When you setup your array, just use the two drives you want in the Array Manager, create the RAID0 and leave the third drive by itself as it's own volume. Some older RAID cards may force you to create a separate RAID array (another RAID0 usually), and use the third drive as the only disk in the array. You may get a better answer than mine if you edit your question and let everyone know what type of RAID card you are using, or if you are setting up an array with software, if the drives are SAS or SATA, etc.