I was running mine in RAID 0 until I started running (the pair plus a third) in RAID 5.As for which is better, that depends on which is more important... a slight performance increase, or a relatively significant increase in data integrity. With the data spread over two drives with no parity, a failure of one drive means a loss of all data. I found this risk to be completely acceptable on my system drive, but not for my data (which was JBOD until I went RAID 5).10,000 RPM drives are significantly faster than 7,200 RPM drives in real world applications. Not only can they read/write faster, they have lower latency - that makes a big difference on small and frequent HD access. There are (and have been for a while) 15,000 RPM drives, but they are only available in SCSI.